ICM v3.8-5 and higher now supports MMTF Format for Large Molecules.
The MMTF binary format allows you to read and display millions of atoms.
molSkin - Publication Quality Surfaces
Publication quality image created using the molSkin option - see documentation.
molSkin - Coloring Surface Molecule Contacts
Publication quality image created using the molSkin option - see documentation.
GPCR Structures Supermimposed
Created using accent feature and clipped macroshape. Structures were superimposed using superimpose button in the display tab.
Adrenergic Receptor PDB:2rh1
Image generated by playing around with the lighting options in the light tab.
Cholera Toxin PDB:1xtc
Image generate using surface option in the Display tab with Sketch Accent (View menu).
ICM Pocket Finder
The ICM Pocket Finder method can find drug like pockets in protein, RNA and DNA molecules.
SYK tyrosine kinase domain with Gleevec PDB:1xbb
Hydrogen bond with receptor shown as spheres and the DFG region colored red. All changes made using the Display tab.
SYK tyrosine kinase domain with Gleevec PDB:1xbb
Receptor pocket surface is shown colored by binding property.
SYK tyrosine kinase domain with Gleevec PDB:1xbb
The ligand pocket is displayed - this representation gives a better indication of where there is space in the pocket to modify your ligand.
