Membrane Optimal Docking Area  

MODA Training and Validation Set

Protein_NameDomainPDBMembrane_Inserting_ResiduesReference
PKCaC21dsyA188:190;247;249:253(Kohout et al., 2003; Verdaguer et al., 1999)
Cytosolic phospholipase A2C21cjyA33:36; 38:39; 62:65; 95:98(Dessen et al., 1999; Frazier et al., 2002; Xu et al., 1998)
Synaptotagmin-1C21rsyA173:177; 232:238(Chae et al., 1998; Frazier et al., 2003; Sutton et al., 1995)
Synaptotagmin-1C21tjxA305:307; 367:369(Cheng et al., 2004; Rufener et al., 2005)
Sec14Sec141auaA218:221; 223:224; 227:228; 230:231(Sha and Luo, 1999; Sha et al., 1998)
Epsin-1ENTH1h0aA1:7; 9:16(Ford et al., 2002)
Coagulation factor VC1czsA2090:2093; 2142:2147(Macedo-Ribeiro et al., 1999)
Coagulation factor VIIIC1d7pM2217:2220; 2268:2272(Pratt et al., 1999)
EEA1FYVE1jocA,B1352:1353; 1365:1371(Dumas et al., 2001; Kutateladze et al., 2004; Kutateladze and Overduin, 2000)
HRSFYVE1dvpA171:175(Mao et al., 2000; Stahelin et al., 2002)
VPS27FYVE1vfyA181:189(Misra and Hurley, 1999; Stahelin et al., 2002)
ThrombinGla1nl2A44:53; 59(Falls et al., 2001; Huang et al., 2003)
p47-phoxPX1o7kA64:69; 77:85(Karathanassis et al., 2002; Stahelin et al., 2003)
p40-phoxPX1h6hA35:36; 58; 60; 92:98(Bravo et al., 2001; Stahelin et al., 2003)
Sgk3PX1xteA76:82(Xing et al., 2004)
SNX3PX1ocuA112:118(Zhou et al., 2003)
PKC-dCys21ptrA239:243; 250; 252:254(Wang et al., 2001; Xu et al., 1997; Zhang et al., 1994)
Cytochrome P450P4501dt6A30:31; 33:34; 36:41; 43:45; 60:63; 68:69; 376:377; 379(Headlam et al., 2003; Williams et al., 2000)
PI-PLCPI-PLC1gymA73:75; 77:78; 268:274(Feng et al., 2002; Heinz et al., 1996)
Ganglioside GM2 activator proteinGM2-AP1tjjA90:95; 160:163(Wright et al., 2003)