Quick_Facts
GYG1A: Human Glycogenin-1
Chaikuad, A., Froese, D.S., Yue, W. W., Krysztofinska, E., von Delft, F., Lee, W.H., Marsden, B.D., Liu. Q., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Oppermann, O.
3Q4S (deposited on 24.Dec.2010)
3QVB (deposited on 24.Dec.2010)
3RMW (deposited on 21.Apr.2011)
3RMV (deposited on 21.Apr.2011)
3T7M (deposited on 30.Jul.2011)
3T7N (deposited on 30.Jul.2011)
3T7O (deposited on 30.Jul.2011)
Datapack version: 2 (built on 23.May.2011; last revised on 08.Sep.2011)
Quick Facts
SGC target ID |
GYG1A |
QUICK FACTS |
Human glycogenin 1 |
Updated |
2011-05-24 |
Domain architecture of solved Structure (Pfam) |

|
Protein Mass |
39.384 kDa |
Number of residues |
350 aa |
Contact info. |
|
Gene ID |
GYG1 |
Genecard |
GYG1 |
cDNA source |
|
Gene sequence |
NM_004130.2 |
Protein sequence |
NP_004121.2 |
Biochemical function |
Unclassified |
Biological function |
- Metabolism
- Energy pathways
|
Human mutations |
OMIM: 603942 |
Mouse models |
|
Summary role in disease |
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Closest sequence matches of solved domain(s) (10 or less) |
Name |
ID% |
Description |
NP_004121.2 |
100. |
glycogenin-1 isoform 1 [Homo sapiens] |
NP_001171649.1 |
100. |
glycogenin-1 isoform 2 [Homo sapiens] |
gi|34783423 |
100. |
GYG1 protein [Homo sapiens] |
gi|119599303 |
100. |
glycogenin 1, isoform CRA_c [Homo sapiens] |
gi|189055328 |
99.71 |
unnamed protein product [Homo sapiens] |
XP_003310161.1 |
99.42 |
PREDICTED: glycogenin-1 isoform 1 [Pan troglodytes] |
XP_516810.3 |
99.39 |
PREDICTED: glycogenin-1 isoform 3 [Pan troglodytes] |
gi|322812775 |
99.23 |
Chain A, Crystal Structure Of Human Glycogenin-1 (Gyg1), Apo Form |
gi|332639932 |
99.23 |
Chain A, Crystal Structure Of Human Glycogenin-1 (Gyg1) T83m Mutant Complexed With Manganese And Udp-Glucose |
gi|67971052 |
99.09 |
unnamed protein product [Macaca fascicularis] |
|
Closest match in PDB (solved domain(s)) |
Name |
ID% |
ICM-pP |
Description |
1LL2 |
89.78 |
59.24 |
Chain A, Crystal Structure Of Rabbit Muscle Glycogenin Complexed With Udp-Glucose And Manganese |
1LL0 |
88.20 |
58.61 |
Chain A, Crystal Structure Of Rabbit Muscle Glycogenin |
1ZCU |
85.14 |
57.30 |
Chain A, Apo Form Of The 162s Mutant Of Glycogenin |
1ZCV |
85.14 |
57.37 |
Chain A, Apo Form Of A Mutant Of Glycogenin In Which Asp159 Is Replaced By Asn |
1ZCY |
85.14 |
57.30 |
Chain A, Apo Form Of A Mutant Of Glycogenin In Which Asp159 Is Replaced By Ser |
1ZCT |
83.79 |
52.68 |
Chain A, Structure Of Glycogenin Truncated At Residue 270 In A Complex With Udp |
|
Splice forms |
ENSG00000163754 |
ProSite hits |
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localization |
|
Protein expression |
- Skeletal muscle
- Heart
- Brain
- Placenta
- Lung
- Liver
- Kidney
- Pancreas
- Leukocyte
|
Substrates/ cofactors/ inhibitors |
|
Interacting proteins |
- GNIP
- Glycogen synthase 1
- Glycogenin 1
- Glycogenin 2
- Nuclear envelope pore membrane protein POM 121
Link to HPRD website |
Posttranslational modifications |
Link to HPRD website |
Key references |
PubMed: 15860684, 15870102, 17311895. |
Other comments |
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