Oct 21 2010 Feedback.
Contents
 
Introduction
How To Guide
Getting Started
Molecular Graphics
Slides and Documents
ActiveICM
Movie Making
Sequences & Alignments
 Load
  SwissProt/UniProt
  Cut and Paste
  Extract from PDB
  From File
 Bioinfo Menu
 Search and Align
 Alignments
 Editor
Protein Structure Analysis
Protein Superposition
Crystallographic Analysis
Homology & Modeling
3D Predict
Molecular Mechanics
Cheminformatics
Chemsitry Menu
Docking
Ligand Editor
Tables
Local Databases
FAQs
Tutorials
 
Index
PrevICM User's Guide
8.1 Load Sequence
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[ SwissProt/UniProt | Cut and Paste | Extract from PDB | From File ]

There are a number of different ways to load a sequence into ICM via the Graphical User Interface.

8.1.1 Read a Sequence from SwissProt


Swissprot is a curated protein sequence database which provides a high level of annotation (such as the description of the function of a protein, its domains structure, post-translational modifications, variants, etc.). Each protein entry has an unique SwissID code associated. To retrieve a Swissprot annotated protein sequence enter the SwissID code and click 'OK'. The annotation can be transferred to a protein structure, providing that the structure has the same sequence (or has been aligned to the retrieved Swissprot sequence)

  • File/Load/SWISSPROT
  • Enter SWISSPROT ID

8.1.2 Cut and Paste a Sequence


Paste your own sequence into ICM

  • File/New/Sequence
  • Paste the Sequence into the box provided.

8.1.3 Extract a Sequence from a PDB File


Extract a Sequence from a PDB file

  • Right click on a loaded PDB file in the ICM Workspace.
  • Select Extract Sequence(s)

8.1.4 Read directly from a Sequence File


Read from file

If you have a sequence file saved in FASTA format it can be read into ICM by:

  • File/Open


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