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Contents
 
Introduction
Help Videos
Reference Guide
Getting Started
Protein Structure
Molecular Graphics
Slides & ActiveICM
Sequences & Alignments
Protein Modeling
 Homology Modeling
 Loop Modeling
 Design Loop
 Graft Loop
 Loop Preferred Residues
 Find PDB Loop Segment
 Regul
 Refine SC
 Make Disulfide Bond
 Make a Mutation
 Modify Amino Acid
 Mutation - Protein Binding
 Mutation - Protein Stability
 Protein Peptide
 Protein Ligand
 Disulfide Bond
 Sculpting
 Sample Protein
 Sample Peptide
 Molecular Mechanics
Cheminformatics
Learn and Predict
Docking
Virtual Screening
Molecular Dynamics
MolScreen
3D Ligand Editor
Tables and Plots
Local Databases
ICM-Scarab
KNIME
Tutorials
FAQs
 
Index
PrevICM User's Guide
9.11 Modify Amino Acid
Next

How to Modify an Amino Acid Group:
To modify a group:
  • Convert your molecule into an ICM Object.
  • Right click on the amino acid residue you wish to modify and choose Edit/Attach Modifier.
  • Click on the molecular editor icon and use the tools in the molecular editor to sketch the modification you want.
  • In the molecule editor right click on the atom which will be the attachment point and select "Attachment Point". An asterisk will be placed on that atom.
  • Close the editor and then click OK in the "Covalently attach a chemical modifier" dialog box (see image above).
  • Choose to minimize the geometry.


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Mutation - Protein Binding

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